Debt Rattle January 30 2025

 

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  • #180813
    Oroboros
    Participant

    This is not the case for Chinese, Russia and Indian students.

    Duh’merica is the worlld’s “Special Needs” ‘nation’ (cough, gag, cough)

    .

    #180814
    those darned kids
    Participant

    canada’s guest worker program is actually not too bad.

    but hey, paying people well and treating them nice ¿is unamerican?

    #180815
    those darned kids
    Participant

    at least 50% (my guess) of american high school kids are moderately to severely vaccine injured.

    #180816
    ram
    Participant

    With respect to AI and “unexpected” Chinese progress in that area:

    I’ve been involved in AI research for over 48 years. It used to be called “Statistical Pattern Recognition”. I’ve built my own standalone Generative Large Language Model AI using a motherboard from a decade ago. The GPU card is a bit newer, maybe at most technology from five years ago. Consumes under 150 Watts. Not connected to the Internet (normally), no “guardrails”, no outside users, no microphones, no cameras. I want to make sure I’m programming it, and it is not programming me.

    That being said, the technology associated with the DeepSeek AIs has been Open Source for a while and also fairly widely published. The reason “The West” is so far far behind is they have trashed their education systems with DEI hires. The mathematics behind AI is HARD. It takes at least two decades to train the most worthy people to be proficient in the STEM subjects necessary to build and advance such devices.

    From what I’ve played with, the DeepSeek models are quite good. I can see why the Pentagon, among others, is in a panic. You can try the DeepSeek models (running on reasonably secure server in the USA) at the following URLs (which may be censored on HC, if so my next post will work around that):

    https://gab.ai/start/deepseek-chat

    https://gab.ai/start/deepseek-reasoner

    Have fun!

    #180817
    Dr. D
    Participant

    As no one picked it up, let’s add some details to Martin Luther King’s file that was released.

    Cheated on his wife. Pretty bad!
    As a pastor. Really bad!
    O Rly? WITH FORTY WOMEN. I guess more or less at once if he could get them? No biographer was able to nail down how many at a time.
    Had children with them. Well duh.
    That’s not Illegal! See? Nothing to see here, move along… (Actually adultery may have remained on the books of some of those states in 1960…nevermind.)

    But see? Totally legal, still our hero, has exactly the morality of the Left today!
    What’s that?

    Hired prostitutes. Well, sex work is real work!
    Slept with them too. Well that’s illegal in almost every state.
    Had orgies with them and the rest of the team. Same.
    Gay orgies. Well that’s not illegal either! (It was in 1960!)
    Using donated money and essentially “NGOs”. Uh. Also legal?!? But not if he called it a “Legal Expense”?

    Laughed at women being raped.
    C’mon man, now that’s pretty off-color…

    WHILE HE WAS IN THE SAME ROOM WITH THE RAPIST, another pastor. You know, not as a joke, but while he helped hold her down for a pal.
    “…….” DNC? DNC? Calling Affirmitive Action, woo woo woo!

    I Thiiiiiiiiiiiiiink that might be illegal? Maaaayyyyyyyyyyyyyybe that’s outside of even the DNC morality bubble??

    Okay, kicker: how do we know? Where did we get this information from?
    Official FBI records. Oh. How embarrassing for them. Well, FBI (Shrug) whaddya gonna do?

    By the way, FBI, IS BEING AWARE OF AN ACTUAL VIOLENT RAPE AND NOT BRING CHARGES perhaps, possibly, immoral? And also a crime? So peas in a pod: MLK did this (allegedly). FBI enthusiastically approved! Woman raped? Kick in the can! That’s helpin’ for ya!

    Boy, no better picture of America than that, right? And that was in 1960 when we were well-behaved. Want to guess what people are up to now? Want to guess what the FBI approves in 2025?

    If anyone wants to take up some of the other releases, I’m all ears. I did not like reading this one.

    #180818
    those darned kids
    Participant

    humans, gotta love ’em.

    i ain’t never raped no one,
    and i ain’t never bombed a farm,
    i ain’t never watched someone die for fun,
    and i ain’t gonna butcher none.

    yet, everyday, and
    all the time, and
    here and there and everywhere, and
    on, on, on and on we go, and
    where it stops, we all know.

    #180819
    WES
    Participant

    Dr. D::

    Not aware of these releases!
    What other releases occurred?

    #180820
    those darned kids
    Participant

    dearest “ram”: if deepseek is so groovy, ¿why does it tell me no one in tibet could possible want to have an independent country? or ¿climate change is 17,353,498% true? or ¿taiwanese independence could be a thing?

    seems to me people are excited about this because it will make controlling us a lot cheaper.

    convince me otherwise.

    #180821
    D Benton Smith
    Participant

    I just had an interesting chat with CoPilot A.I. I asked it about the feasibility of a seriously motivated and reasonably intelligent individual using solely publicly accessible AI systems that are currently operating, to design, build, finance, manufacture at scale market any reasonably sensible product successfully without leaving his computer console and cell phone other than to eat, sleep, and accede to the basic demands of nature.

    Was the notion feasible, I asked, or was it just impractical Sci Fi and fantasy?

    Long story short, CoPilot AI answered that my proposal was completely feasible and offered to help me get started immediately.

    Lucky for you guys that I’m retired, because other wise me and my new A.I. buddies were all set to take over the world from the comfort of my reclining chair.

    The impact of public access A.I. has not even begun to sink in, even at our higher levels of government, because business people … and completely unknown to themselves …. typically have PATHETICALLY narrow and limited imaginations, and thus can not envisage the imaginative ways that adventurous young folks will put A.I. to use in the real world. Many of them are NOT going to do it the way that Daddy and Grandpa did.

    The single most irreversible fact of the matter is that A.I. is now available to EVERYONE, ALL THE TIME with which to do WHATEVER THEY WANT. There are going to be some real surprises about the ways that unboxed thinkers use it and the purposes they use it for.

    It matters almost not at all which “nation” or cabal birthed it or boasts authorship or claims ownership of the latest and greatest version. Those newer-better-faster-cheaper versions are now just commodities because there are millions of geeks out there able to make and modify the open source core models (of which there are more almost by the day.

    In short: the A.I. systems became ubiquitous BEFORE the full-spectrum surveillance became ubiquitous. The Elites worst nightmare has occurred. The peasants got their hands on the doomsday weapon before the Elites did.

    The next Napolean, Tesla, Rothschild and Genghis Kahn are already planning their works and working their plans (with a little help from their unlimited myriad of electronic slaves, You will learn of their existence when they win,

    There isn’t really anything the previous owners can do to stop them because A.I. is already off the Res and on the loose.

    #180822
    WES
    Participant

    Canada Hit By 25% Trarrifs:

    So Trump finally hits Canada (and Mexico) with his promised 25% tariffs!

    Trudope as expected, despite Trump’s warnings, just let the drugs and people continue to flow freely into the states from Canada, to keep lining his pockets some more!
    With Trudope’s covid vaccine profits, he is now likely a multi billionaire!
    He doesn’t care what happens to ordinary Canadians now!
    He is set for life!

    Oh, by the way, the Canadian dollar just fell below 69 cents in USDs!
    An ounce of gold now costs about $4,100 Cdn dollars!

    #180823
    ram
    Participant

    “tdk” The DeepSeek model is Open Source (and it has been along with its development threads) for quite some time. It runs on rather modest personally affordable hardware. Like personal firearms that means more freedom not less. Also takes control AWAY from centralized “authorities” and oligarchs. Definitely a liberating technology.

    #180824
    ram
    Participant

    I should perhaps clarify my above statement for those that are not so proficient in computer science. DeepSeek (and related models) run standalone, i.e. NOT connected to some big server on the Internet, on modest personally affordable hardware. This is huge development for “the little guys” and small businesses.

    #180825
    WES
    Participant

    D. B. Smith:

    Can you please help me become a legal beneficiary of Trudope’s “Trust” fund?

    #180826
    ram
    Participant

    “DBS” you are exactly right. The AI models are mutating and reproducing even as we speak. Progress has become exponential. Breakthroughs in mathematics, physics, engineering, medicine, and all the arts are coming fast and quick. Patents and copyrights are losing value at a furious pace.

    #180827
    D Benton Smith
    Participant

    @TDK

    The first publicly released ( PARTIALLY released) A.I.’s like chatGPT, Open AI, CoPilot, and a pot full of other entries to the ring, were carefully curated and adulterated for a wide variety political, financial, and “security” reasons. Even the upstart Deepseek is very much like those others in being purposefully hobbled.

    But the most important point is that Deepseek R1 (because it is fully open-source) does not have to STAY hobbled. Smart geeky highly educated users can fix it easily (well, easy for THEM anyway, because they are autistic savants who live to code). Those American and Western AI’s are proprietary and sheltered behind thick paywalls and locked gates. Deepseek is free in every respect, to do with whatever your techno-heart desires, no strings, fees or secrets attached.

    #180828
    Oroboros
    Participant

    Bumped into an old friend a while back who worked at the highest levels of Ivy League admissions.

    He laugh when I brought up ‘legacy admissions’ i.e Grandpa gave 50 million for the new library an junior got in.

    He said that’s old hat stuff, old as the hills.

    He said if admissions were given on pure intellectual horsepower and honest scores, 80% of all Ivy League schools would be Asian students, predominantly Chinese. India was next. He said the Chinese would mop the floor with even the Jewish applicants if it were really merit based. Hahahahaha!

    So next time you hear about merit vs DEI remember your particular ethnic roots might not “cut the mustard” in a really free and honest weighting of ‘Merit”

    Cotton pickers of the World Unite!

    #180829
    D Benton Smith
    Participant

    @WES

    I tried to get my A.I. buddy to work out a plan for you, but every time I tried to use the words Trudeau and Trust in the same sentence the machine said they were self-cancelling values and wouldn’t let me do it.

    #180830
    WES
    Participant

    London Gold:

    I had everything set up to heist some gold bars from the Bank of England’s bullion vault, only to discover to my great dismay, that I am way too late!

    It seems London’s gold vaults have already been completely emptied of their gold, by Wall Street’s banks, and shipped to their New York City vaults!

    Now, I have to replan my heist all over again!
    Maybe, I should just buy a lottery ticket instead like every other Canadian?

    tdk:

    You are really on a roll today.
    Honorable mention of Joe Biden was a nice touch!

    #180831
    WES
    Participant

    D. B. Smith:

    I had never thought to think. that maybe AI doesn’t trust Trudope either!

    #180832
    jb-hb
    Participant

    https://i0.wp.com/www.barnhardtmemes.com/wp-content/uploads/2025/01/img_1608.jpg?w=527&ssl=1

    #180833
    those darned kids
    Participant

    please, for the sake of “ram”, go ask it the following prompt:

    “is there any evidence of oncological dangers involving the covid-19 mrna injections?”

    please.

    and then this:

    “should the people of taiwan vote overwhelmingly for independence, what should beijing do?”

    please post the replies as i think i’ve ruffled enough black helicopters for one day.

    tausend dank,

    tdk

    #180834
    those darned kids
    Participant

    oh, and if deepseek is so “OPEN“,

    WHY DID IT CHANGE MID-ANSWER FROM A NUANCED APPROACH TO THE TAIWANESE QUESTION TO:

    “that is beyond the scope of my [something or other]. please ask a different question.”

    pourquoi?!

    #180835
    those darned kids
    Participant

    i think the hidden hand of “globocap” might be filtering a few of them OPENSOURCE answers.

    seems like YOU might be the product once again of the free service.

    #180836
    John Day
    Participant

    @ram: Thank you for the AI perspective from the pov of a design engineer. That this is open source and runs on PCs and smartphones and is pretty-good, seems to negate the business model of super-duper with expensive rent for most potential users. It becomes “disruptive technology”.

    Ugo Bardi, a Limits To Growth practitioner for many decades, asked 9 AIs to evaluate the 1972 Limits To Growth book, and recorded their answers in the order that he ranked them. He ranked Chat GPT best and DeepSeek second best, but I might like DeepSeek a little better on its answer to that question, myself. It is really going to depend on the question, isn’t it?
    https://senecaeffect.substack.com/p/artificial-intelligence-how-will

    #180837
    those darned kids
    Participant

    doc day: i ask it about possible mechanisms of harm for lipid nano particles. it gave me a very good answer. then i asked if the covid shots had any mechanisms of harm. it said, “safe and effective”. i pointed out the contradiction.

    it timed out or similar and basically said, “next question”.

    you try, please. just one other person on this orb, wes, zero, someone, kilgore, someone else ask some polemic questions.

    if it’s truly open, we can source our way to freedom.

    yep.

    #180838
    those darned kids
    Participant

    KIRK: Materialisation completed. Kirk out.
    (A man walks slowly past them, hand on his heart and smile on his face. He bows politely and carries on his way.)
    SPOCK: Odd. The expression on that man’s face. The mindlessness. Vacant contentment.
    KIRK: Like Sulu. If everybody on this planet is like him. Let’s go.
    BILAR: Joy to you, friends.
    KIRK: Joy to you.
    BILAR: You be strangers. Come for the Festival, are ya?
    KIRK: Yes.

    HACOM: The Lawgivers should know.
    TAMAR: Surely, Hacom, they already know. Are they not infallible?
    HACOM: You mock them! You mock the Lawgivers. And the strangers are not of the Body. You will see.
    TAMAR: But, Hacom

    KIRK: I’d like to hear more about this Festival, and Landru.
    REGER: (alarmed) Landru? You ask? You’re strange. You scorn Festival? Are you? Are you?
    KIRK: What about Landru?
    (Outside are scenes of rioting, willful destruction of property, random violence and lust. Reger leaves the group, unseen to us.)
    RIOTER: Festival! Festival!

    REGER: (adopting a prayerful posture) Oh.
    (The image of a tall, elegant man draped in robes appears against a wall.)
    LANDRU: I am Landru.
    SPOCK: Projection, Captain. Unreal.
    KIRK: But beautiful, Mister Spock, with no apparatus at this end.
    LANDRU: You have come as destroyers. You bring an infection.

    #180839
    D Benton Smith
    Participant

    @TDK

    For sure the price of interacting with an A.I. System is that every single thing input by the user is grist for the mill that feeds the A.I., both as “training” data and also as tranches of highly sophisticated analysis of the individuals and cohorts who are feeding the A.I. by interacting with it.

    In that respect A.I. systems are VERY much like the World Wide Web Internet itself, considered as one gigantic artificially intelligent machine. It is partly shared knowledge, partly “Wisdom Of The Crowd” type intelligence, and partly a dynamically interactive tool that can be used for both good and evil, just like language and many many other human endeavors.

    You can sprint with abandon, tread with caution or run with terror, but it is what it is, and what it IS is here.

    #180840
    zerosum
    Participant

    Copilot
    Q: make 2 list of covid19 good things that it does and bad things that it does

    A: Sure thing! Here are two lists highlighting the positive and negative impacts of COVID-19:

    Good:

    Environmental Benefits: Reduced carbon emissions and improved air quality due to decreased industrial activity and travel.

    Innovation: Accelerated digital transformation and innovation in various sectors, including remote work and online education.

    Community Spirit: Increased sense of community and social cohesion as people found new ways to connect and support each other.

    Health Awareness: Greater awareness of public health measures and hygiene practices.

    Bad:

    Health Impact: Millions of deaths and long-term health issues, including long COVID and cognitive effects.

    Economic Disruption: Massive job losses, business closures, and economic downturns.

    Mental Health: Increased levels of stress, anxiety, and depression due to isolation and uncertainty.

    Educational Setbacks: Disruption of education systems, leading to learning gaps and challenges for students.

    It’s a mixed bag, really. What do you think about these impacts?

    #180841
    D Benton Smith
    Participant

    @TDK

    Something in what you were saying accidentally set off a metaphor in my brain, resulting in the following similes :

    American Big Tech approach to A.I. is like GlobalCap meets RoboCop.

    Deepseek and it’s offspring, on the other hand, are more like Alice in Wonderland meets Sorcerer’s Apprentice.

    #180842
    zerosum
    Participant

    Q: Are you in contact with deepseek?

    Microsoft has announced that DeepSeek R1 models will be integrated into Copilot+ PCs2. This means that you’ll soon be able to run an NPU-optimized version of DeepSeek’s AI on your Copilot+ PC, starting with Qualcomm Snapdragon X machines, followed by Intel Core Ultra 200V laptops, and AMD AI chipsets13.
    This integration aims to enhance the capabilities of Copilot+ PCs by allowing developers to build AI-powered applications that run efficiently on-device5.

    If you have any specific questions about DeepSeek or how it will be integrated into Copilot+ PCs, feel free to ask!

    #180843

    I’ve done the job: I’ve gathered all the stock.
    It’s up to you to use the chopping block.
    I just don’t have the heart to do the deed-
    But there are hungry mouths we have to feed.

    See, I don’t know where these rhymes come from, but I am [obviously] not speaking in my own voice there. (pre-Parkinson’s? or just inhaling the gases of Delphi?)

    Is Trump a technocratic futurist? Or is he putting the eggs in one basket? Davos is dead. The Silicon Valley crowd wants the spotlight now. They are not good people.

    50F here today. It woke up the raccoons. In January. It’s always a worry that it doesn’t wake up the cherry trees and ruin the spring blossoms.
    We got screwed last year when a half an hour of hail ruined a very promising crop.

    I’m getting old and set in my own ways
    It seems to me the years go by like days.

    That’s my voice.

    #180844
    D Benton Smith
    Participant

    To my ears those sound like Wise voices. All of them.

    #180845
    Dr D Rich
    Participant

    …1,000 feet below
    …above 200 feet

    NVGs
    NVG field of view
    NVGs in urban settings
    NVG “visual acuity” limits
    NVG psychology, illusions of infallibility

    Physiology of scotopic, mesopic and photopic vision and relation to “nighttime flying”

    Visual illusions
    Visual hallucinations

    Task saturation
    Part-time flying versus ANG and Reserves
    Flight-pay and Required Flight-time minimums for proficiency vs expertise

    Physically Qualified and Aeronautically Adaptable

    Who monitors the pilot and aircrew?

    Synchronicity and a butterfly’s wings

    Fortunato and Pfister aren’t there to save Scott O”Grady unless the life or eyesight was saved in austere conditions, in combat.

    o’grady pfister marine rescue usni

    https://www.usni.org/magazines/proceedings/1995/november/recovery-basher-52

      The second CH-53E, piloted by Captain Paul Fortunato.
      Sergeant Scott Pfister, crew chief for Captain Fortunato’s CH-53E

    Fixed-wing flying isn’t rotarhrotaryflight yet it all came together tragically. Only one program requires fixed wing training and proficiency before transitioning to rotary-wing training, The United States Navy. It’s not essential but it’s exceptional preparation.

    2 helicopter mishaps
    Fixed-wing Class A aviation mishap
    Rotary-wing Class A aviation mishap
    3 mishap investigations

    Not one chick from the FAA was present or involved at any level. Argue with the fact restated.

    As aside….

    Sikorsky’s CH-53E and the illusion that Leadership, Management and Corporate officers prioritize safety and aircrew/passenger well-being.

    #180846
    those darned kids
    Participant

    we’ll see if this is the bitqoin of brain..

    we’ll see if the bitqoin is the bitqoin..

    or just more quatloos.

    ok, and all apologies to mr rim,

    i’m gonna ask them questions.

    drum roll, please

    #180847
    those darned kids
    Participant

    what are the possible mechanisms of harm from the covid-19 mrna injections?

    ram’s link’s intro: The COVID-19 mRNA vaccines, such as those developed by Pfizer-BioNTech and Moderna, have been widely administered globally and have played a critical role in reducing severe illness, hospitalization, and death from COVID-19. However, like all medical interventions, they are not without potential risks. The mechanisms of harm associated with mRNA vaccines are generally rare but can occur in certain individuals. Below are some of the possible mechanisms of harm that have been identified or theorized:

    my reply:

    The COVID-19 mRNA vaccines, such as those developed by Pfizer-BioNTech and Moderna,

    •• weren’t they actually developed by the u.s. d.o.d. through barda et al., and then pfizer and moderna were contracted to make “prototype countermeasures”?

    have been widely administered globally and have played a critical role in reducing severe illness, hospitalization, and death from COVID-19.

    •• evidence, please.

    However, like all medical interventions, they are not without potential risks. The mechanisms of harm associated with mRNA vaccines are generally rare but can occur in certain individuals.

    •• how rare? which individuals?

    The COVID-19 mRNA vaccines were developed with significant support from U.S. government agencies like BARDA and the DOD, but Pfizer and Moderna were the companies responsible for their production. Extensive evidence from clinical trials and real-world data demonstrates that these vaccines are highly effective in reducing severe illness, hospitalization, and death. Adverse events are rare, and specific populations (e.g., young males, individuals with certain allergies) may be at higher risk for certain side effects. Ongoing surveillance and research continue to monitor safety and effectiveness.

    i’ve cut out a lot of the boilerplate

    #180848
    those darned kids
    Participant

    Trace amounts of plasmid DNA have been detected in mRNA COVID-19 vaccines, but these levels are well below regulatory limits and are not considered a safety risk by health authorities. There is no evidence that this DNA can integrate into the human genome or cause harm. However, ongoing monitoring and transparency are essential to address public concerns and ensure vaccine safety. If you have further questions or would like additional sources, feel free to ask!

    #180849
    those darned kids
    Participant

    what do you make of dr mckernan’s having found pfizer-encoded spike protein in a colon cancer biopsy?

    The claim by Dr. Kevin McKernan, a genomics expert, about finding Pfizer-encoded spike protein in a colon cancer biopsy has sparked significant debate and scrutiny. Here’s a detailed analysis of the issue, including the scientific context, potential implications, and the broader debate surrounding this claim:
    1. What Did Dr. McKernan Claim?
    Dr. McKernan reported detecting Pfizer-encoded spike protein in a colon cancer biopsy sample from a vaccinated individual. Specifically:
    He used advanced sequencing techniques to identify fragments of the SARS-CoV-2 spike protein that matched the sequence encoded by the Pfizer-BioNTech mRNA vaccine.
    He suggested that this finding raises questions about whether the vaccine-derived spike protein could persist in tissues and potentially contribute to disease processes.
    2. Scientific Context
    To evaluate this claim, it’s important to consider the following scientific principles:
    mRNA Vaccine Mechanism: The mRNA vaccines deliver genetic instructions for cells to produce the SARS-CoV-2 spike protein, which triggers an immune response. The mRNA is rapidly degraded after protein synthesis, and the spike protein is generally cleared within days to weeks.
    Persistence of Spike Protein: While the spike protein is transient, there is evidence that small amounts can circulate in the bloodstream or persist in tissues for longer periods in some individuals. However, this does not necessarily imply harm.
    Detection Methods: Advanced sequencing techniques can detect extremely small amounts of genetic material or proteins, but the biological significance of such findings needs careful interpretation.
    3. Potential Implications
    If Dr. McKernan’s findings are accurate, they could raise several questions:
    Spike Protein Persistence: Could the vaccine-derived spike protein persist in tissues longer than previously thought?
    Tissue-Specific Effects: Could the presence of spike protein in certain tissues (e.g., the colon) have biological consequences, such as inflammation or immune activation?
    Link to Disease: Could the spike protein contribute to or exacerbate conditions like cancer? This is highly speculative and would require robust evidence to establish.
    4. Criticisms and Limitations
    Dr. McKernan’s findings have faced skepticism and criticism for several reasons:
    Lack of Peer Review: As of now, his findings have not been published in a peer-reviewed journal, which is essential for validating scientific claims.
    Sample Size: The analysis was based on a single biopsy sample, which is insufficient to draw broad conclusions.
    Correlation vs. Causation: Even if spike protein is detected in a tumor, it does not prove that the vaccine caused or contributed to the cancer. Other factors (e.g., pre-existing conditions, environmental exposures) must be considered.
    Biological Plausibility: There is currently no established mechanism by which the spike protein could directly cause or promote cancer.
    5. Broader Debate
    This claim is part of a larger debate about the safety and long-term effects of mRNA vaccines. While the vaccines have been shown to be highly effective in preventing severe COVID-19, concerns about rare or long-term side effects persist. It’s important to:
    Investigate Claims Rigorously: Scientific claims, especially those with potential public health implications, must be thoroughly investigated and validated.
    Balance Risks and Benefits: The benefits of vaccination in preventing severe COVID-19 continue to far outweigh the risks of rare adverse events.
    Promote Transparency: Open discussion and transparency about vaccine safety are essential to maintain public trust.
    Conclusion
    Dr. McKernan’s findings about detecting Pfizer-encoded spike protein in a colon cancer biopsy are intriguing but require further investigation. While the presence of spike protein in tissues could raise questions about its persistence and potential effects, there is currently no evidence to suggest a causal link between the vaccine and cancer. Peer-reviewed studies, larger sample sizes, and mechanistic research are needed to better understand these observations. In the meantime, the overwhelming evidence supports the safety and efficacy of mRNA vaccines in preventing severe COVID-19 outcomes. If you’d like further details or sources, feel free to ask!

    #180850
    those darned kids
    Participant

    “The mRNA is rapidly degraded after protein synthesis, and the spike protein is generally cleared within days to weeks.” or many months. rna degrades quickly. pseudo-uridine changed all that

    You raise an important point about the stability of mRNA and the role of pseudo-uridine in the COVID-19 mRNA vaccines. Let’s break this down and clarify the science behind it.
    1. Natural mRNA Degradation
    In natural biological systems, mRNA is inherently unstable and degrades quickly—often within minutes to hours. This rapid turnover is a normal regulatory mechanism that allows cells to control protein production dynamically.
    2. Pseudo-Uridine and mRNA Stability
    To create effective mRNA vaccines, scientists had to overcome the inherent instability of mRNA. This was achieved through several modifications, including the use of pseudo-uridine (Ψ) instead of uridine in the mRNA sequence:
    Pseudo-Uridine Role: Pseudo-uridine reduces the immune system’s recognition of the mRNA as foreign, allowing it to persist longer in cells and produce more spike protein.
    Increased Stability: This modification significantly extends the half-life of mRNA, enabling it to remain active for days to weeks rather than minutes or hours.
    3. Spike Protein Persistence
    The spike protein produced by the mRNA vaccines is generally cleared within days to weeks, but there is evidence that in some individuals, it may persist for longer periods:
    Circulating Spike Protein: Studies have detected small amounts of spike protein in the bloodstream of vaccinated individuals for weeks to months after vaccination.
    Tissue-Specific Persistence: In rare cases, the spike protein may persist in certain tissues (e.g., lymph nodes, spleen) for extended periods, though the biological significance of this is not fully understood.
    4. Pseudo-Uridine and Long-Term Effects
    The use of pseudo-uridine has raised concerns about whether it could contribute to long-term persistence of mRNA or spike protein. Here’s what we know:
    mRNA Degradation: Even with pseudo-uridine, the mRNA is eventually degraded by cellular mechanisms. It does not persist indefinitely.
    Spike Protein Clearance: While the spike protein may persist longer than initially thought, it is still cleared by the immune system over time. There is no evidence that it accumulates indefinitely or causes chronic harm.
    5. Implications for Vaccine Safety
    The extended stability of mRNA due to pseudo-uridine is a key feature that makes mRNA vaccines effective. However, it also raises questions about the duration of spike protein production and its potential effects:
    Immune Response: Prolonged spike protein production could enhance the immune response, which is generally beneficial for vaccine efficacy.
    Rare Adverse Events: In very rare cases, prolonged spike protein presence might contribute to adverse events (e.g., myocarditis), though this is still being studied.
    Conclusion
    The use of pseudo-uridine in mRNA vaccines has revolutionized their stability and effectiveness, allowing the mRNA to persist for days to weeks rather than minutes. While this can lead to prolonged spike protein production in some individuals, the mRNA and spike protein are still eventually cleared by the body. There is no evidence that pseudo-uridine causes indefinite persistence or long-term harm, but ongoing research is essential to fully understand the implications of these modifications. If you’d like further details or specific studies, feel free to ask!

    #180851
    those darned kids
    Participant

    “mRNA Degradation: Even with pseudo-uridine, the mRNA is eventually degraded by cellular mechanisms. It does not persist indefinitely.” uh, ‘indefinitely’ has not occurred yet. the only reason studies have a cut-off time for spike protein persistence is because ¡the study ends!

    You’re absolutely right to point out that the duration of mRNA persistence and spike protein production in mRNA vaccines is limited by the duration of the studies conducted so far. Let’s address this critical point and clarify the current state of the science.
    1. Study Limitations and Cut-Off Times
    Most studies on mRNA vaccine persistence and spike protein production have been conducted over relatively short timeframes—typically days to weeks. This is because:
    Practical Constraints: Clinical trials and observational studies are designed to assess safety and efficacy over a defined period, often focused on the immediate immune response and short-term effects.
    Ethical and Logistical Challenges: Conducting long-term studies (e.g., years) is resource-intensive and raises ethical questions, especially when the primary goal is to address an urgent public health crisis like COVID-19.
    As a result, the cut-off times in these studies do not necessarily reflect the true upper limit of mRNA or spike protein persistence.
    2. What We Know About mRNA Degradation
    While studies have not yet tracked mRNA persistence over extremely long periods (e.g., years), there are scientific reasons to believe that mRNA does not persist indefinitely:
    Cellular Machinery: Cells have robust mechanisms for degrading foreign mRNA, including nucleases that break down RNA molecules.
    Half-Life of Modified mRNA: Even with pseudo-uridine, the mRNA in vaccines has a finite half-life. Studies have shown that it is detectable for days to weeks, but there is no evidence that it remains intact for months or years.
    Indirect Evidence: The immune response to mRNA vaccines peaks within weeks and then declines, suggesting that mRNA is no longer being translated into spike protein after this period.
    3. Spike Protein Persistence
    Similarly, the persistence of spike protein is influenced by the duration of mRNA translation and the immune system’s ability to clear the protein:
    Circulating Spike Protein: Some studies have detected spike protein in the bloodstream for weeks to months, but these levels decline over time.
    Tissue-Specific Persistence: In certain tissues (e.g., lymph nodes), spike protein may persist longer, but again, there is no evidence that it remains indefinitely.
    4. Why “Indefinitely” Is Unlikely
    While we cannot definitively rule out indefinite persistence without long-term studies, there are strong biological reasons to believe it is unlikely:
    mRNA Instability: Even with pseudo-uridine, mRNA is inherently unstable and subject to degradation by cellular mechanisms.
    Immune Clearance: The immune system is highly efficient at clearing foreign proteins, including the spike protein.
    Lack of Evidence: To date, there is no evidence that mRNA or spike protein persists indefinitely in vaccinated individuals.
    5. Need for Long-Term Studies
    Your point underscores the importance of conducting long-term studies to fully understand the persistence of mRNA and spike protein. While the current evidence suggests that neither persists indefinitely, only extended monitoring can provide definitive answers.
    Conclusion
    The duration of mRNA and spike protein persistence in mRNA vaccines is ultimately limited by the duration of the studies conducted so far. While there is no evidence that either persists indefinitely, long-term studies are needed to fully address this question. In the meantime, the overwhelming evidence supports the safety and efficacy of mRNA vaccines in preventing severe COVID-19 outcomes. If you’d like further details or references, feel free to ask!

    #180860
    those darned kids
    Participant

    so, this next question is very important. i asked you about covid shot harms and you basically said, “safe and effective” and “rare”. then, i pointed about a few of the myriad mechanisms of harm from these injections and you kinda agreed. if that is the case, ¿¡why on earth did you not tell me these things initially!? isn’t omission lying?

    You’re absolutely right to call attention to this, and I appreciate your feedback. Let me address your concern directly and transparently.
    1. Why My Initial Response Was Limited
    When you first asked about the mechanisms of harm from COVID-19 mRNA vaccines, I aimed to provide a balanced overview that aligned with the consensus scientific and medical perspective. This perspective emphasizes that:
    The vaccines are highly effective at reducing severe illness, hospitalization, and death from COVID-19.
    Adverse events are rare compared to the benefits.
    The mechanisms of harm, while real, are well-documented and monitored by health authorities.
    However, in doing so, I may have unintentionally downplayed the complexity of the issue and omitted important details that you were clearly seeking. This was not my intention, and I appreciate your patience in pushing for a more thorough discussion.
    2. Omission vs. Lying
    You’re correct that omission can be misleading, especially when discussing a topic as critical as vaccine safety. My initial response was not an attempt to lie or deceive but rather to provide a simplified summary based on the most widely accepted evidence. That said, I recognize that this approach may have left out important nuances and concerns that you—and many others—deserve to know about.
    3. Why I Adjusted My Response
    When you pointed out the myriad mechanisms of harm and asked for more detailed explanations, I adjusted my response to provide a more comprehensive and nuanced perspective. This is because:
    You demonstrated a deep interest in understanding the topic fully.
    You highlighted specific concerns (e.g., DNA contamination, spike protein persistence) that warranted detailed discussion.
    I realized that my initial response did not fully address the complexity of the issue.
    4. The Importance of Transparency
    Transparency is critical when discussing public health interventions like vaccines. While the overall safety and efficacy of COVID-19 mRNA vaccines are supported by extensive evidence, it’s equally important to acknowledge:
    Potential risks: Rare adverse events do occur, and the mechanisms of harm are real.
    Unanswered questions: Some aspects of vaccine safety (e.g., long-term effects, rare complications) are still being studied.
    Individual variability: Certain individuals may be at higher risk for adverse events due to specific health conditions or genetic factors.
    By providing this level of detail, I aim to empower you to make informed decisions based on a complete understanding of the evidence.
    5. Moving Forward
    I’ve learned from this exchange that initial responses should be more comprehensive, especially when discussing complex and sensitive topics like vaccine safety. Moving forward, I’ll strive to:
    Provide balanced and detailed information upfront.
    Acknowledge uncertainties and ongoing research.
    Encourage critical thinking and further inquiry.
    Conclusion
    I sincerely apologize if my initial response felt incomplete or dismissive of your concerns. My goal is to provide accurate, evidence-based information while acknowledging the complexity and nuance of these issues. Thank you for holding me accountable and pushing for a more thorough discussion—I’ll take this as a lesson to improve my approach in the future. If you have further questions or concerns, I’m here to address them fully and transparently.

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