DPC City Hall subway station, New York 1904
Scariest bit today? Here it is:
— James Gallagher (@JamesTGallagher) March 23, 2020
• Cases 391,947 (+ 46,654 from yesterday’s 345,292)
• Deaths 17,138 (+ 2,213 from yesterday’s 14,925)
From Worldometer yesterday evening (before their day’s close)
One look at the US suffices. It was up 9,293 at 42,893. So far today another 2,434 were added, total now 46,168. Death toll yesterday was 522, now 582.
From Worldometer -NOTE: mortality rate for closed cases is at 14% !! 2 weeks ago it was at 6%-
Just today, March 24, two more deaths from the Diamond Princess were announced. The last crew members left the ship March 1.
The coronavirus survived for up to 17 days aboard the Diamond Princess cruise ship, living far longer on surfaces than previous research has shown, according to new data published Monday by the Centers for Disease Control and Prevention. The study examined the Japanese and U.S. government efforts to contain the COVID-19 outbreaks on the Carnival-owned Diamond Princess ship in Japan and the Grand Princess ship in California. Passengers and crew on both ships were quarantined on board after previous guests, who didn’t have any symptoms while aboard each of the ships, tested positive for COVID-19 after landing ashore.
The virus “was identified on a variety of surfaces in cabins of both symptomatic and asymptomatic infected passengers up to 17 days after cabins were vacated on the Diamond Princess but before disinfection procedures had been conducted,” the researchers wrote, adding that the finding doesn’t necessarily mean the virus spread by surface. “COVID-19 on cruise ships poses a risk for rapid spread of disease, causing outbreaks in a vulnerable population, and aggressive efforts are required to contain spread,” the CDC wrote, reiterating its guidance to vulnerable populations to avoid cruises during the pandemic.
[..] The new study set out to determine how “transmission occurred across multiple voyages of several ships.” They noted that as of March 17, there were at least 25 cruise ship voyages with confirmed COVID-19 cases that were detected either during or after the cruise ended. Almost half, 46.5%, of the infections aboard the Diamond Princess were asymptomatic when they were tested, partially explaining the “high attack rate” of the virus among passengers and crew. [..] The researchers found that 712 of 3,711 people on the Diamond Princess, or 19.2% were infected by COVID-19.
And why wouldn’t this be true everywhere?
Note: the -unrelated- explainer video is pretty much a must see
Nearly half of the Diamond Princess cruise ship passengers and crew who tested positive for the novel coronavirus were asymptomatic at the time they were tested, according to a new report from the US Centers for Disease Control and Prevention. Of the 712 passengers and crew members of the ship who tested positive for coronavirus, 331 – or 46.5% – were asymptomatic at the time of testing, the CDC said. The agency said that the high rate of asymptomatic infections could partly explain the high rate of infection among cruise ship passengers and crew.
Traces of the virus were found “on a variety of surfaces in cabins of both symptomatic and asymptomatic infected passengers up to 17 days after cabins were vacated on the Diamond Princess but before disinfection procedures had been conducted,” the CDC said. However, the surface contamination on the ship can’t be used to determine whether transmission occurred from contaminated surfaces without further study, the CDC cautioned. As of March 13, 107, or 25%, of the 428 Americans on the Diamond Princess tested positive for coronavirus, the agency said.
What coronavirus symptoms look like, day by day pic.twitter.com/k4IVK4QX2m
— Tech Insider (@techinsider) March 18, 2020
Italian newspaper La Repubblica apparently reports that infection rate in Italy is 10x higher than acknowledged. I like the tweeted response:
“That’s actually good news (if true). Death rate much lower and also means everyone has it.”
If everyone’s infected, there’s no more need for lockdowns.
Italy’s number of new Covid-19 cases dropped to a five-day low on Monday, easing tension on overstretched hospitals and bringing a glimmer of hope to a nation that has lost more lives than any other country to the pandemic. In Spain, however, more people died in the last 24 hours than at any point since the coronavirus outbreak erupted in what has become Europe’s second most devastated country. Italian health authorities announced 4,789 new cases in the last 24 hours, a drop from 5,560 on Sunday and 6,557 on Saturday. It was also lower than the levels of Thursday and Friday, when the figures for confirmed cases were still rising. The number of hospitalised cases in Lombardy – the Italian region enduring the most serious outbreak – also declined for the first time since the contagion took root.
“Today is perhaps the first positive day we have had in this hard, very tough month,” said Giulio Gallera, the top health official in Lombardy, an area known as the economic engine of Italy. “It is not the time to sing victory, but we are beginning to see the light at the end of the tunnel.” The number of coronavirus cases in Italy has risen to 63,927 – compared to 81,093 in mainland China. [..] The overall death rate from the pandemic in Italy has further risen to 9.5 per cent, far exceeding the global average of 4.4 per cent. Of the confirmed cases, 3,204 were in intensive care, while 26,522 were under home quarantine.
The US went from 409 cases two weeks ago to 46,000 now, sure to cross the 100,000 line in a few days, i.e. in under 3 weeks. This “study” claims this could take almost 2 months in India.
India could face between around 100,000 and 1.3 million confirmed cases of the disease caused by the new coronavirus by mid-May if it continues to spread at its current pace, according to a team of scientists based mainly in the United States. The estimates reinforce concerns among some medical officials and experts in India that the country of 1.4 billion people could see coronavirus cases jump sharply in the coming weeks and put its health system under severe strain. The scientists said projections could change as the country conducts more testing, while also putting in place stricter restrictions and measures to stem the spread of the virus.
“Even with the best case scenarios, probably, you are in a very painful crisis,” said Bhramar Mukherjee, a professor of biostatistics and epidemiology at the University of Michigan who was involved in the study. The study was carried out by the COV-IND-19 Study Group of scholars and scientists looking into the threat posed by the coronavirus, and COVID-19, the disease it causes, in India. [..] India probably has only around 100,000 intensive care unit (ICU) beds and 40,000 ventilators, said Dhruva Chaudhry, president of the Indian Society of Critical Care Medicine, based on industry estimates and other data. “We can handle it if an even number (of cases) come over a period of time,” Chaudhry said. But he warned that there was not sufficient infrastructure or staff to handle a sharp spike in critical patients.
[..] So far, India has reported 471 cases of the coronavirus and 9 deaths, numbers dwarfed by countries like China, Italy and Spain, but which are nonetheless beginning to accelerate. Authorities have imposed a lockdown across large parts of the country, including in the capital city New Delhi and the financial hub of Mumbai. The original study was based on data up to March 16, but following a request from Reuters, the team updated their model using cases from Indian health authorities up to March 21.
Yeah, this stinks. But it’s not a “coronavirus treatment”. Remdesivir is an antiviral that’s alleged to be effective against Ebola and Marburg.
This afternoon, the Food and Drug Administration granted Gilead Sciences “orphan” drug status for its antiviral drug, remdesivir. The designation allows the pharmaceutical company to profit exclusively for seven years from the product, which is one of dozens being tested as a possible treatment for Covid-19, the disease caused by the new coronavirus. Experts warn the designation, reserved for treating “rare diseases,” could block supplies of the antiviral medication from generic drug manufacturers and provide a lucrative windfall for Gilead Sciences, which maintains close ties with President Donald Trump’s task force for controlling the coronavirus crisis. Joe Grogan, who serves on the White House coronavirus task force, lobbied for Gilead from 2011 to 2017 on issues including the pricing of pharmaceuticals.
“The Orphan Drug Act is for a rare disease and this is about as an extreme opposite of a rare disease you can possibly dream up,” said James Love, the director of Knowledge Ecology International, a watchdog on pharmaceutical patent abuse. “They’re talking about potentially half the population of the United States,” said Love, adding that “it’s absurd that this would happen in the middle of an epidemic when everything is in short supply.” The 1983 Orphan Drug Act gives special inducements to pharmaceutical companies to make products that treat rare diseases. In addition to the seven-year period of market exclusivity, “orphan” status can give companies grants and tax credits of 25 percent of the clinical drug testing cost. The law is reserved for drugs that treat illnesses that affect fewer than 200,000 people in the U.S.
But a loophole allows drugs that treat more common illnesses to be classified as orphans if the designation is given before the disease reaches that threshold. As of press time, there were more than 40,000 confirmed cases of Covid-19 in the U.S, and some 366,000 worldwide. The distinction could severely limit supply of remdesivir by granting Gilead Sciences exclusive protection over the drug and complete control of its price. Other pharmaceutical firms, including India-based pharmaceutical firm Cipla, are reportedly working towards a generic form of remdesivir, but patients in the U.S. could be prevented from buying generics with lower prices now that Gilead Sciences’ drug has been designated an orphan.
The distinction could severely limit supply of remdesivir by granting Gilead Sciences exclusive protection over the drug and complete control of its price. Other pharmaceutical firms, including India-based pharmaceutical firm Cipla, are reportedly working towards a generic form of remdesivir, but patients in the U.S. could be prevented from buying generics with lower prices now that Gilead Sciences’ drug has been designated an orphan. Today, Gilead abruptly announced that it would no longer provide emergency access to remdesivir, telling the New York Times that “overwhelming demand” left it unable to process requests for the drug through its compassionate use program. Hours later, the Food and Drug Administration gave the drug orphan status. Almost immediately, Gilead’s stock price shot up.
Okay, I’m confused. Time for Dr. John Day and other medical commentariat to chime in. This suggests the “human” version’s generic name is hydroxychloroquine, but when we started discussing it here 5 weeks ago, we were talking about chloroquine phosphate, which the article says is for fish only.
Also, we don’t read how much these people took. And the woman is critical but still does elaborate interviews?
An Arizona man has died after ingesting chloroquine phosphate — believing it would protect him from becoming infected with the coronavirus. The man’s wife also ingested the substance and is under critical care. The toxic ingredient they consumed was not the medication form of chloroquine, used to treat malaria in humans. Instead, it was an ingredient listed on a parasite treatment for fish. The man’s wife told NBC News she’d watched televised briefings during which President Trump talked about the potential benefits of chloroquine. Even though no drugs are approved to prevent or treat COVID-19, the disease caused by the coronavirus, some early research suggests it may be useful as a therapy.
The name “chloroquine” resonated with the man’s wife, who asked that her name not be used to protect the family’s privacy. She’d used it previously to treat her koi fish. “I saw it sitting on the back shelf and thought, ‘Hey, isn’t that the stuff they’re talking about on TV?'” The couple — both in their 60s and potentially at higher risk for complications of the virus — decided to mix a small amount of the substance with a liquid and drink it as a way to prevent the coronavirus. “We were afraid of getting sick,” she said. Within 20 minutes, both became extremely ill, at first feeling “dizzy and hot.” “I started vomiting,” the woman told NBC News. “My husband started developing respiratory problems and wanted to hold my hand.”
She called 911. The emergency responders “were asking a lot of questions” about what they’d consumed. “I was having a hard time talking, falling down.” Shortly after he arrived at the hospital, her husband died. [..] On Monday, Banner Health, based in Arizona, said the couple took the additive called chloroquine phosphate. The couple unfortunately equated the chloroquine phosphate in their fish treatment with the medication —known by its generic name, hydroxychloroquine ..
One coin, two sides.
People across the US have come forward to call the anti-malaria drug a ‘miracle’ coronavirus treatment as New York state officials announce they will start trials with the medication on Tuesday. On Monday, New York Gov. Andrew Cuomo said the state will doctors will start trialing hydroxychloroquine this week after the number of coronavirus cases in New York City alone rose to 12,000, an increase of more than 3,000 overnight. The drug has not yet been proven as effective in battling the virus, but President Donald Trump drummed up excitement over it when he called it a ‘game changer’ last week. Dr Anthony Fauci, the White House coronavirus expert, said more work was needed before it could be heralded as a solution. But people like Rio Giardinieri, Margaret Novins and Lost star Daniel Dae Kim are praising the drug for saving their lives.
Giardinieri, who is the vice-president of a company that manufactures cooking equipment for high-end restaurants in Los Angeles, said his doctors administered the drug as a last hope for his recovery. The 52-year-old believes he contracted the virus during a conference in New York and immediately fell ill with a fever for five days, back pain, headaches, a cough and fatigue. ‘I was at the point where I was barely able to speak, and breathing was very challenging,’ he told Fox 6. He went to Joe DiMaggio Hospital in South Florida, where doctors diagnosed him with pneumonia and coronavirus. Giardinieri explained that he was placed on oxygen but he was still unable to breath. After a week, doctors told him there was nothing else they could do and on Friday evening he said goodbye to his wife and three children.
‘I really thought my end was there. I had been through nine days of solid pain and for me, the end was there, so I made some calls to say, in my own way, goodbye to my friends and family,’ he told the news site. Giardinieri said a friend then told him about the anti-malaria drug. He immediately asked a doctor to administer the medication. He then explained what came next, including the moment when he felt like his heart was beating out of his chest. ‘They had to come in, and get me calmed down, and take care of me,’ Giardinieri said. But then the next morning he says he ‘woke up like nothing ever happened’ and feeling much better. The doctors said they don’t believe Giardinieri’s episode was a reaction to the anti-malaria drug but instead was likely the virus progressing in his body. ‘To me, the drug saved my life,’ Giardinieri said.
Keep distance everywhere except in parliament? There are pictures of UK nurses in overloaded London subway trains. Because the risk of infection at work is not high enough, I guess.
The decision to shut down parliament until August goes against the entire underpinnings of our Westminster political democracy. The argument that it practically needs to happen is just rubbish. Parliament kept operating through both World Wars. It operated during the Great Depression and even the Spanish Influenza of 1919. In those days we didn’t have the technology nor know-how we do today to make it even easier to keep parliament open, whether from a transport or communications perspective. The same reason that well prepared private schools have seamlessly moved to online learning systems is the reason the nation’s parliament could operate — at the very least — as a virtual chamber if necessary. Or as it did this week with social distancing and limited attendance.
What message does it send culturally that parliament is apparently so irrelevant it can pack up until the second half of the year without concern? Our democracy is not about the executive running the joint without parliamentary oversight — especially in times of crisis when scrutiny and accountability become even more important. While parliament inevitably includes no small degree of buffoonery, the role of Question Time and the platform the chamber gives individual MPs to voice the concerns of their local communities is vital. As are the committee processes.
Shouldn’t everyone be doing this? Where are governments’ purchases of 3D printers?
Amid the COVID-19 pandemic, Ecuador has become the second worst-hit country in the region with over 980 infected as of Monday and with the rapid spread of the virus the country now faces a severe shortage of personal protective equipment (PPE) for its health workers. Yet this grim reality became an opportunity for a group of Ecuadoreans business owners and enthusiasts of 3-D printing to join together and apply their knowledge to produce much-needed equipment for the doctors and nurses fronting the virus. “As soon as the news came, we started to think and talk about ways to help…we saw there was a need for protective gear and realized we could help,” Mateo Arcos, co-coordinator of the Hacking COVID-10 EC initiative told teleSUR.
The group began with 60 volunteers that decided to produce face shields, which are PPEs that provide over the top, side, and front face protection against splash and splatter of fluid-borne pathogens. Now the initiative has over 280 volunteers. The decision to opt for this was based on the fact many medical personel across the country were cutting off plastic bottles in order to make their own masks, crippling health workers’ ability to respond to the coronavirus pandemic. “There is a clear scarcity of it so we opted to make them, also as it was the more viable option,” Arcos added.
Imagine the earth protecting herself from mankind by debilitating its powers to destroy her any further.
Italy has gone full “Wuhan” with a massive lockdown across the country amid a virus crisis that has paralyzed its economy. So far, 63,927 confirmed cases of COVID-19 had been reported, with 6,077 deaths. The Italian economy is being dragged into a depression as the fast-spreading virus cripples its northern regions, forcing the government to ban travel and close all industrial production across the country. The impact of the virus on Italy’s economy led to the collapse of electricity consumption last week. Electricity usage fell 16% YoY for March 16-22, according to Bloomberg calculations based on Terna SpA data.
Diego Marquina, an analyst covering European power markets at BloombergNEF, noted on Monday that electricity demand in every European country has declined due to the impact of quarantine measures to mitigate the virus spread. Marquina said if declining electricity consumption is “sustained…weekday power demand would most likely fall to Sunday levels – a 10-26% reduction, depending on the country.” He estimates that power prices could drop between 6-18 EUR/MWh.
Fortune magazine explained the motivation behind China’s propaganda push: “For China, the outreach to Europe is part of an effort to claw back an international leadership role after early cover-ups helped the virus spread well beyond its borders. President Xi Jinping’s government has sought to silence critics, including reporters and online commentators, and also spread conspiracy theories about where the virus originated. “Geopolitically, China’s move to brand itself as Europe’s savior aims to improve its standing on a global stage as both spar with the Trump administration. China and the U.S. have continued a wider fight for global influence — Beijing kicked out more than a dozen American journalists this week — while also seeking to deflect blame for their handling of the disease.”
On March 12, China sent to Italy a team of nine Chinese medical staff along with some 30 tons of equipment on a flight organized by the Chinese Red Cross. The head of the Italian Red Cross, Francesco Rocca, said that the shipment “revealed the power of international solidarity.” In recent days, China has also sent aid to:
• Greece, March 21. An Air China plane carrying 8 tons of medical equipment — including 550,000 surgical masks and other items such as protective equipment, glasses, gloves and shoe covers — arrived at Athens International Airport. The Chinese Ambassador to Greece, Zhang Qiyue, referred to words by Aristotle: “What is a friend? A single soul living in two bodies.” He said that “difficult times reveal true friends” and that China and Greece are “working closely together in the fight against the coronavirus.” This, he said, “confirms once again the excellent relations and friendship between the two peoples.”
• Serbia, March 21. China flew six doctors, ventilators and medical masks to Serbia to help Belgrade halt spreading of the coronavirus infection. “A big thank you to President Xi Jinping, the Chinese Communist Party and the Chinese people,” said Serbian President Aleksandar Vucic. China’s ambassador to Belgrade, Chen Bo, said the aid was a sign of the “iron friendship” between the two countries.
• Spain, March 21. The founder and president of the Chinese technology company Huawei, Ren Zhengfei, donated one million face masks. They were expected to arrive at Zaragoza Airport in northeastern Spain on March 23. The masks will be stored at a warehouse belonging to the Spanish apparel retailer Zara. From there, Zara will put its logistics network at the service of the Spanish government.
• Czech Republic, March 21. A Ukrainian cargo plane reportedly carrying 100 tons of medical supplies from China arrived at the airport in Pardubice, a city situated 100 kilometers east of Prague. On March 20, a Chinese plane carrying one million masks arrived in the Czech Republic, which reportedly ordered another 5 million respirators from China along with 30 million masks and 250,000 sets of protective clothing.
• France, March 18. China sent to France, the second-most powerful country of the European Union, a batch of medical supplies, including protective masks, surgical masks, protective suits and medical gloves. The Chinese Embassy in France tweeted: “United we will win!” The following day, China sent a second batch of supplies. The Chinese Embassy tweeted: “The Chinese people are next to the French people. Solidarity and cooperation will allow us to overcome this pandemic.”
• The Netherlands, March 18. China Eastern Airlines, China Southern Airlines and Xiamen Airlines, codeshare partners with KLM Royal Dutch Airlines, donated 20,000 masks and 50,000 gloves. The shipment arrived at Amsterdam Airport Schiphol on a Xiamen Airlines flight. “These are extremely difficult times for our country and our company, so we are very happy with this help for KLM and for the Netherlands,” KLM CEO Pieter Elbers said. “Less than two months ago, KLM made a donation to China and now we are being helped so wonderfully and generously.”
• Poland, March 18. The Chinese government pledged to send Poland tens of thousands of protective items and 10,000 coronavirus test kits. On March 13, the Chinese Embassy in Warsaw sponsored a videoconference during which experts from China and Central Europe shared their knowledge on tackling the coronavirus.
• Belgium, March 18. A Chinese cargo plane carrying 1.5 million masks landed at Liege Airport. The masks, which will be distributed to Belgium, France and Slovenia, were donated by Jack Ma, the founder of Alibaba, a Chinese ecommerce giant known as the “Amazon of China.”
• Czech Republic, March 18. A plane carrying 150,000 test kits for coronavirus landed in Prague. The Ministry of Health paid about CZK 14 million ($550,000) for 100,000 testing kits, while another 50,000 kits were paid for by the Ministry of the Interior. Transport was provided by the Ministry of Defense.
• Spain, March 17. A Chinese plane carrying 500,000 masks arrived at Zaragoza Airport. “The sun always rises after the rain,” Chinese President Xi Jinping told Spanish Prime Minister Pedro Sánchez. He said that the friendship between China and Spain will be stronger and bilateral ties will have a brighter future after the joint fight against the virus. Xi said that after the pandemic, both countries should intensify exchanges and cooperation in a wide range of fields.
• Belgium, March 16. Another shipment of medical supplies donated by the Jack Ma Foundation and Alibaba Foundation for epidemic prevention in Europe arrived at Liege Airport.
“Italy is not alone…
I thank the Russian Federation, President Putin, and the government for all the support they are showing.”
— Italian Foreign Minister Luigi Di Maio
— Sarah Abdallah (@sahouraxo) March 23, 2020
Unlimited purchases announced and stocks tank. Is that the end of the line?
With its announcement this morning, the Fed expanded its three fundamental mechanisms in which it is once again bailing out the biggest risk takers, over-leveraged companies, hedge funds, mortgage REITs, and PE firms; wiping out cash-flows for crash-averse savers and holders of Treasury securities; and creating special opportunities for well-connected individuals who have access to the Fed’s programs. And let’s get this straight: None of the programs are going to fix the economy.
These bailout programs fall into three mechanisms:
1. Fed buys assets directly. Until this morning, this was limited to Treasury securities, agency debt, and residential MBS backed by Ginnie Mae (US government agency) and the GSEs, Freddie Mac and Fannie Mae. This morning, the Fed added agency-backed commercial mortgage-backed securities (CMBS) to the list.
2. Fed sets up special purpose vehicles (SPV) and lends to the SPVs which then buy assets or lend. These SPVs can buy assets the Fed is not allowed to buy and they can lend to entities and individuals to buy certain assets. Under the Federal Reserve Act, these SPVs require taxpayer backing from the Treasury Department to protect the Fed from losses.
3. The Fed lends to its 24 Primary Dealers against collateral, and that collateral can be anything the Fed decides, including now stocks – and in the end finally old bicycles.
The entire alphabet soup of new programs will take a while to get set up and get started. And since they won’t fix the economy and its underlying problems, they might not work as well in accomplishing their goals – making the wealthy wealthier – as they did during the Financial Crisis. So we’ll have to see how this works out.
1979: I bet there’ll be flying cars in the future
— You Have One Job, Stay Indoors (@_youhadonejob1) March 23, 2020
BREAKING: Assange’s lawyers have announced that they will be applying for bail at court this Wednesday, 25 March. They argue that he is in imminent danger from Coronavirus spreading through the prison population and should be released for his and other prisoners and staff safety. pic.twitter.com/pVjglPPi80
— Don't Extradite Assange (@DEAcampaign) March 23, 2020
Fr. Giuseppe Berardelli, a 72-year-old priest who gave a respirator (that his parishioners had purchased for him), to a younger patient (whom he did not know), has died from #coronavirus.
— James Martin, SJ (@JamesMartinSJ) March 24, 2020
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