DPC Grand Central Station and Hotel Manhattan, NY 1906
• Cases 311,796 (+ 32,476 from yesterday’s 279,320)
• Deaths 13, 071 (+ 1,481 from yesterday’s 11,587)
I dubbed it “Virus Time” myself, but even my brain has trouble comprehending what that truly is. It’s been less than two days since I wrote:
“My prediction: The US has overtaken France, and will in the next few days pass Germany, Spain, and then Iran.”
Less than 48 hours later, it’s done. This is what things looked like the day before I said that:
And here we are this morning:
Difference in timing of emergency declarations between San Francisco and Miami-Dade:
The virus still is a time machine. Project the next two weeks:
Here are the usual graphs. Note: I replaced the last one, COVID2019.app, with COVID2019Live.info, because the former keeps on closing off access.
From Worldometer yesterday evening (before their day’s close)
From Worldometer -NOTE: mortality rate for closed cases is at 12% !! –
From SCMP: (SCMP appears to have given up on timely updating)
From COVID2019Live.info: (Replacement for COVID2019.app, which -again- had their pages closed)
first publicly recorded case in China is the first case? We would have to say very close to zero. If the first publicly recorded case is the first actual case that would just as a matter of medical practice in China (and TBF other even developed countries) be very unlikely 2/n
— Social Distancing Balding 大老板 (@BaldingsWorld) March 22, 2020
One higher probability scenario in that the virus has been circulating for much longer in China and making its way abroad for far longer. I think the evidence increasingly fits the idea this is much more wide spread than is currently acknowledged.
— Social Distancing Balding 大老板 (@BaldingsWorld) March 22, 2020
That’s real wartime measures. Contrast it with Germany politely asking its car manufacturers to produce medical equipment. Everyone’s waiting till the very last moment, and that’s always too late. But that’s politicians for you, and we’re not going to change that anytime soon.
• Italy To Shut All Non-Strategic Business Activities Until April 3 (R.)
Prime Minister Giuseppe Conte said on Saturday that all Italian businesses must close until April 3, with the exception of those essential to maintaining the country’s supply chain, in the latest desperate effort to halt the coronavirus epidemic. Italy recorded a jump in deaths from the virus of almost 800 on Saturday, taking the toll in the world’s hardest-hit country to almost 5,000. “It is the most difficult crisis in our post-war period,” Conte said in a video posted on Facebook, adding that “only production activities deemed vital for national production will be allowed”.
Supermarkets, pharmacies, postal and banking services will remain open, Conte said, and essential public services including transport will be ensured. “We are slowing down the country’s production engine but we are not stopping it,” he said. The government is expected to publish an emergency decree on Sunday to make the latest crackdown immediately effective.
So let them roam free for 10 hours a day, and that should solve what exactly?
• India Starts 14-Hour Curfew To Curb Virus Spread (R.)
India launched a 14-hour curfew on Sunday (March 22) to limit the fast-spreading coronavirus epidemic in the country, where 315 people have so far been found to have contracted the disease. Prime Minister Narendra Modi, in an address to the nation last week, urged citizens to stay indoors from 7am to 9pm local time – a move that he said would be a crucial test for a country to assess its abilities to fight the pandemic. “Let us all be a part of this curfew, which will add tremendous strength to the fight against the Covid-19 menace,” Mr Modi tweeted minutes before the curfew commenced. “The steps we take now will help in the times to come.” Health experts said India’s cases have been growing at a rate seen during the early stages of the outbreak in other countries, which subsequently reported exponential increases in infections.
Several Indian states announced measures to curb the spread of coronavirus. Four cities in Mr Modi’s home state of Gujarat have declared a complete shutdown until Wednesday. The neighbouring desert state of Rajasthan ordered a shutdown until March 31, while eastern and central states suspended inter-state bus operations to prevent an exodus of daily wage earners from urban centres to villages. State leaders urged citizens not to rush to villages and avoid crowding trains and buses to prevent the virus spread. Tensions have mounted, however, with angry labourers protesting at some bus stations against sudden closures of basic transport services.
Funny they don’t say who gets to be tested, and who doesn’t. Until we know, what’s the difference with today?
• FDA Approves New Coronavirus Test That Can Diagnose Within Hours (Solomon)
The Food and Drug Administration announced approval Saturday for a new coronavirus test that can diagnose patients within hours, instead of days. The new rapid test, manufactured by California-based Cepheid, is expected to be in the market by March 30, officials said. “The test we’re authorizing today will be able to provide Americans with results within hours, rather than days like the existing tests,” Health and Human Services Secretary Alex Azar said. “With the development of point of care diagnostics, Americans who need tests will be able to get results faster than ever before.
“More and more options for reliable, convenient testing are becoming available at an incredibly rapid pace, thanks to the hard work of our FDA team and the ingenuity of American industry.” FDA Commissioner Stephen Hahn said the approval “marks an important step in expanding the availability of testing and, importantly, rapid results.” Hahn said because the rapid test can be administered at the point of care, it “means that results are delivered to patients in the patient care settings, like hospitals, urgent care centers and emergency rooms, instead of samples being sent to a laboratory.”
Tell the braindead on the Florida beaches that. I was thinking: let them get infected, good riddance. But they will infect others too, and besides, shouldn’t the blame rest with Florida state for leaving the beaches open, with the stores and bars for serving them, and with the parents who send their kids into the infection pools?
• Most Cases In New York City Are Of People Under 50 (NBC)
Most people who have tested positive for coronavirus in New York City are younger than 50, according to figures released by the city Saturday. This does not reflect the ages of those who have died, only people confirmed to be infected with the virus. Overall, 57 percent of those who have tested positive in the city are 49 or younger. People 18 to 49 years old make up the majority, 54 percent, the city said. The next largest group are those age 50 to 64, who account for 23 percent of positive test results so far. The accounting reflects data known to the city through 5:30 p.m. Friday. On Friday, New York City Mayor Bill de Blasio said, “We are now the epicenter of this crisis” in the United States.
About 2.5 million people are incarcerated in the US.
• 38 Positive For Coronavirus In NYC Jails, Including Rikers (AP)
At least 38 people have tested positive for coronavirus in New York City jails, including at the notorious Rikers Island jail complex, the board that oversees the city’s jail system said Saturday. In a letter to criminal justice leaders, Board of Correction interim chairwoman Jacqueline Sherman wrote that at least 58 other people were currently being monitored in contagious disease and quarantine units. “It is likely these people have been in hundreds of housing areas and common areas over recent weeks and have been in close contact with many other people in custody and staff,” Sherman warned, predicting a sharp rise in the number of infections.
“The best path forward to protecting the community of people housed and working in the jails is to rapidly decrease the number of people housed and working in them.” In the past six days, she wrote, the board learned that at least 12 Department of Correction employees, five Correctional Health Services employees, and 21 inmates have tested positive for the virus. The city’s jail agency and its city-run healthcare provider did not respond to messages seeking comment on the letter. On Friday, the city’s Department of Corrections said just one inmate had been diagnosed with coronavirus, along with seven jail staff members.
Of all the failing “world leaders”, Boris is vying for the no. 1 position. This came one day after he refused to close pubs and schools.
What triggered him is this: “UK yesterday saw total deaths reach 233. Italy was at exactly that figure on March 7th. 2 weeks behind.”
• Britain ‘Two Or Three Weeks’ Behind Italy On Coronavirus: PM Johnson (R.)
Britain was only “two or three” weeks behind Italy on the spread of coronavirus, Prime Minister Boris Johnson said. In comments carried in the Sunday Telegraph and other Sunday newspapers, Johnson said Britain’s health service could be overwhelmed. “Unless we act together, unless we make the heroic and collective national effort to slow the spread – then it is all too likely that our own NHS will be similarly overwhelmed,” he said.
Turning around on a dime with no mea culpa whatsoever should really boost people’s confidence in you.
• NHS Could Be Overwhelmed Like Italy – Boris (R.)
Britain’s National Health Service (NHS) could be “overwhelmed” by the coronavirus like the Italian health system in just two weeks, Prime Minister Boris Johnson has warned. The death toll in Italy reached almost 5,000 on Saturday, while in the UK it hit 233. In comments carried in the Sunday Telegraph and other Sunday newspapers, Johnson again urged Britons to stay at home to stop the spread of the virus. “Unless we act together, unless we make the heroic and collective national effort to slow the spread – then it is all too likely that our own NHS will be similarly overwhelmed,” he said. “The Italians have a superb health-care system. And yet their doctors and nurses have been completely overwhelmed by the demand,” Johnson noted.
He advised people to keep away from elderly parents on Mothering Sunday (March 22). “The single best present that we can give … is to spare them the risk of catching a very dangerous disease,” he said. Earlier, Britain urged 1.5 million people identified by the NHS as being at higher risk of severe illness if they contract coronavirus to not leave their homes to protect themselves. On Friday, Johnson effectively closed down the United Kingdom, ordering pubs, restaurants, theatres, cinemas and gyms to shut their doors to fight the virus. Stores are also starting to shut.
Also from f#*king Boris. And I kid you not: in the corner of my eye I see a BBC show called “The Big Questions”, in which people who all sit the “correct” 10 feet or so apart, discuss the urgent issue: “Should fat-shaming be against the law?”, as their health system is set to crash. And I’m thinking: those glaciers can’t melt fast enough.
• Doctors Given New Guidelines On Choosing Which Patients To Treat (Ind.)
New guidelines have been published to help doctors and nurses decide how to prioritise patients during the coronavirus pandemic. The advice from the National Institute for Health and Care Excellence (Nice) was produced amid concerns that the NHS would be overwhelmed by the demand for intensive care beds and ventilators. It follows reports from the worst-hit parts of Italy where older and sicker patients had to be rejected in favour of the younger and fitter. The three new Nice guidelines, which have been drawn up within a week rather than the usual timescale of up to two years, cover patients needing critical care, kidney dialysis and cancer treatment.
They say all patients admitted to hospital should still be assessed as usual for frailty “irrespective of Covid-19 status”. Decisions about admitting patients to critical care should consider how likely they are to recover, taking into account the likelihood of recovery “to an outcome that is acceptable to them”. Doctors are advised to discuss possible “do not resuscitate” decisions with adults who are assessed as having increased frailty, such as those who need help with outside activities or are dependent for personal care. The document says critical care treatment should be stopped “when it is no longer considered able to achieve the desired overall goals”, following a discussion with family, carers, the patient or an independent advocate.
“If there was a meteor racing towards earth right now, they would be passing a bill to give that meteor a tax credit.”
• Airlines Appear To Come Up Short In Bid To Win Cash Grants In Rescue Package (R.)
A last-ditch effort by the chief executives of major U.S. airlines to try to win cash grants to weather the coronavirus crisis looked to be unsuccessful, four congressional aides and airline officials said late Saturday. Airlines had made a last ditch plea urging that $29 billion of $58 billion sought in assistance for airlines be in the form of cash grants. They had offered not to make any job cuts through Aug. 31 if they won the cash and to accept restrictions on executive pay and to forgo paying dividends or stock buybacks. The CEOs of 10 U.S. passenger and cargo carriers had said in a letter that without direct cash assistance, “draconian measures” such as furloughs may be necessary.
Senate Republicans hope to unveil the text of the rescue and stimulus package Sunday that could total $1.6 trillion and is set to include $50 billion in collateralized loan and loan guarantees for passenger airlines and $8 billion for cargo carriers. Senate Democratic Leader Charles Schumer said there was still “no deal,” so it is possible the final airline provisions could change in negotiations. Senator John Thune, the Senate’s No. 2 Republican, said earlier airline grants were not winning backing “at this point, I don’t sense support for it here or with the administration. But like I said, nothing is done.”
Airlines are expected to soon turn their attention to applying for government collateralized loans and the terms the legislation will include. The initial Republican plan said the U.S. Treasury could demand stock, warrants or options as part of any airline loans. The global coronavirus outbreak has forced airlines to cancel tens of thousands of flights and resulted in massive revenue losses. On Saturday, United Airlines said it was canceling 90% of its international flights in April.
It’s been obvious for a long time that Americans have completely lost sight of what a hero is. But even then. Pay them a decent salary, then we can talk.
The article is the picture painted for you. The reality is:
“I have been coming in sick because I’m worried that I’ll lose my job or just be punished if I call out,” said Angel Duarte, a package handler at a UPS hub in Tucson, Ariz. “I am 23, and I have no savings, and I have a 4-month-old son.“
• Grocery Clerks Unlikely Heroes In US Coronavirus Fight (R.)
For Philip, a grocery store clerk, it’s not a matter of if he gets coronavirus, but when. He is among millions of supermarket employees who have been classified as critical U.S. workers at “essential businesses” that will stay open to prevent disruption in food supply. While other workers are being told to stay home to slow the spread of the coronavirus, these employees are being asked to put themselves in constant contact with the public. Coronavirus cases are beginning to appear among them. Whole Foods Market on Thursday reported a positive case in a New York City worker.
California late on Thursday issued an unprecedented statewide “stay at home order” directing the state’s 40 million residents to hunker down in their homes for the foreseeable future. Grocery stores, along with pharmacies, banks and gas stations, will remain open under the order. Working low-paying jobs, these unlikely heroes in the produce section and behind the meat counter are both terrified and gratified to be on the frontlines of the U.S. coronavirus fight. Some employers have raised wages and granted paid sick leave, but there is pressure on them to do more.
“I didn’t sign up to be in a position where I’m constantly exposed to a deadly virus, but I understand too that if grocery stores close then there are way bigger problems,” said Philip, who works in the produce section of a Whole Foods store in a southern U.S. state. Philip asked that his last name and location not be used. “I’d just like to get the virus now, and get it out of the way, so I can come back to work,” said Philip, who is in his 30s. “Everyone’s terrified there, deep down, apart from the few who think it’s not a big deal yet.”
Got a letter that says I'm an essential employee, and a paycheck that says I'm not.
— jake merch (@jakefm) March 20, 2020
Words? Not me.
• Banks Pressure Health Care Firms To Raise Prices On Drugs, Supplies (IC)
In recent weeks, investment bankers have pressed health care companies on the front lines of fighting the novel coronavirus, including drug firms developing experimental treatments and medical supply firms, to consider ways that they can profit from the crisis. The media has mostly focused on individuals who have taken advantage of the market for now-scarce medical and hygiene supplies to hoard masks and hand sanitizer and resell them at higher prices. But the largest voices in the health care industry stand to gain from billions of dollars in emergency spending on the pandemic, as do the bankers and investors who invest in health care companies.
Over the past few weeks, investment bankers have been candid on investor calls and during health care conferences about the opportunity to raise drug prices. In some cases, bankers received sharp rebukes from health care executives; in others, executives joked about using the attention on Covid-19 to dodge public pressure on the opioid crisis. Gilead Sciences, the company producing remdesivir, the most promising drug to treat Covid-19 symptoms, is one such firm facing investor pressure. Remdesivir is an antiviral that began development as a treatment for dengue, West Nile virus, and Zika, as well as MERS and SARS.
The World Health Organization has said there is “only one drug right now that we think may have real efficacy in treating coronavirus symptoms” — namely, remdesivir. The drug, though developed in partnership with the University of Alabama through a grant from the federal government’s National Institutes of Health, is patented by Gilead Sciences, a major pharmaceutical company based in California. The firm has faced sharp criticism in the past for its pricing practices. It previously charged $84,000 for a yearlong supply of its hepatitis C treatment, which was also developed with government research support. Remdesivir is estimated to produce a one-time revenue of $2.5 billion.
Just days after the EU accused Russia of using the virus to spread disinformation in Europe.
• Russia Ready to Send 100 Specialists Including Virologists to Italy (Sp.)
“In accordance with instructions from the Russian Defence Minister, Army Gen. Sergei Shoigu, the Russian Aerospace Forces have completed the creation of a necessary air group to deliver forces and equipment from the Russian Defence Ministry allocated to assist the Italian Republic in the fight against the coronavirus”, the statement says. The ministry added that nine Il-76 military transport aircraft with trained crews had been transferred to the Chkalovsky military airfield in the Moscow Region from the Pskov, Ulyanovsk, and Orenburg regions.
The group of about 100 people, including experienced virologists and epidemiologists, is ready to depart for Italy, the ministry said. On Saturday, Russian President Vladimir Putin told Italian Prime Minister Giuseppe Conte by phone that Moscow was ready to promptly assist Rome in the fight against the coronavirus. The defence ministry then said that Russia would send eight mobile teams of Russian military virologists and doctors, vehicles for aerosol disinfection, and medical equipment to Italy.
For your daily group discussion,. WHich you’re not allowed to have anymore.
• The Coronavirus Did Not Escape From A Lab. Here’s How We Know. (LiveScience)
As the novel coronavirus causing COVID-19 spreads across the globe, with cases surpassing 284,000 worldwide today (March 20), misinformation is spreading almost as fast. One persistent myth is that this virus, called SARS-CoV-2, was made by scientists and escaped from a lab in Wuhan, China, where the outbreak began. A new analysis of SARS-CoV-2 may finally put that latter idea to bed. A group of researchers compared the genome of this novel coronavirus with the seven other coronaviruses known to infect humans: SARS, MERS and SARS-CoV-2, which can cause severe disease; along with HKU1, NL63, OC43 and 229E, which typically cause just mild symptoms, the researchers wrote March 17 in the journal Nature Medicine. “Our analyses clearly show that SARS-CoV-2 is not a laboratory construct or a purposefully manipulated virus,” they write in the journal article.
Kristian Andersen, an associate professor of immunology and microbiology at Scripps Research, and his colleagues looked at the genetic template for the spike proteins that protrude from the surface of the virus. The coronavirus uses these spikes to grab the outer walls of its host’s cells and then enter those cells. They specifically looked at the gene sequences responsible for two key features of these spike proteins: the grabber, called the receptor-binding domain, that hooks onto host cells; and the so-called cleavage site that allows the virus to open and enter those cells. That analysis showed that the “hook” part of the spike had evolved to target a receptor on the outside of human cells called ACE2, which is involved in blood pressure regulation. It is so effective at attaching to human cells that the researchers said the spike proteins were the result of natural selection and not genetic engineering.
© Andriy Onufriyenko/Getty Images
Here’s why: SARS-CoV-2 is very closely related to the virus that causes severe acute respiratory syndrome (SARS), which fanned across the globe nearly 20 years ago. Scientists have studied how SARS-CoV differs from SARS-CoV-2 — with several key letter changes in the genetic code. Yet in computer simulations, the mutations in SARS-CoV-2 don’t seem to work very well at helping the virus bind to human cells. If scientists had deliberately engineered this virus, they wouldn’t have chosen mutations that computer models suggest won’t work. But it turns out, nature is smarter than scientists, and the novel coronavirus found a way to mutate that was better — and completely different— from anything scientists could have created, the study found.
Another nail in the “escaped from evil lab” theory? The overall molecular structure of this virus is distinct from the known coronaviruses and instead most closely resembles viruses found in bats and pangolins that had been little studied and never known to cause humans any harm. “If someone were seeking to engineer a new coronavirus as a pathogen, they would have constructed it from the backbone of a virus known to cause illness,” according to a statement from Scripps.
German doctor, during plague in 14th century:
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